4. Development of the complement-fixation test Mackie TJ, Finkelstein MH. J Hyg 1930; 30: 1–24

Detection of rotavirus by Latex Agglutination Test (Rotales); Comparison with Electron Microscopy and Complement Fixation Test

Evaluation of the gonococcal complement-fixation test.

The gonococcal complement-fixation test (GCFT), based on the same principle as the Wassermann reaction (WR), has been in use for over 60 years. The test was applied for the first time, using a culture of the gonococcus as antigen, by Muller and Oppenheim (1906) to establish the diagnosis in a case of arthritis. Teague and Torrey (1907) suggested that negative results in the GCFT were due to dif...

Quantitative micro-complement fixation test.

A quantitative micro-complement fixation test capable of detecting nanogram quantities of antigen is described. The test is simple to perform and is highly reproducible. Typical results from three antigen-antibody systems are given.

A Complement-Fixation Test for Kala-Azar

A Complement Fixation Test for Poliomyelitis

A macroscopic (tube) complement fixation test for poliomyelitis, using infected tissue culture fluids, is described. The test was applied to 27 individuals with a clinical diagnosis of poliomyelitis. In 18 patients it was possible to make a laboratory diagnosis of poliomyelitis on the basis of a rise in complement-fixing antibody titer and in 4 others on the basis of a high stationary antibody ...